What to expect on a timeline when taking testosterone for health optimization.
| Weeks 1-4 | Improved energy levels, alertness, and initial mood stabilization (reduced irritability, anxiety, and depressive symptoms). Sexual interest and morning erections may begin to increase. |
| Months 1-3 | More pronounced improvements in mood, motivation, and sexual desire (libido). Initial gains in muscle mass and strength may become noticeable, especially with exercise. |
| Months 3-6 | Significant improvements in body composition (increased lean muscle, decreased fat mass) and continued enhancement of sexual function. Insulin sensitivity may also improve. |
| Months 6-12+ | Stabilization of major effects. Continued improvements in bone mineral density, cognitive function, and long-term metabolic and cardiovascular markers. |